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Immunoregulation in Health and Disease - Experimental and Clinical Aspects
von: Miodrag L. Lukic, Miodrag Colic, Marija Mostarica-Stojkovic (Eds.)
Elsevier Trade Monographs, 1997
ISBN: 9780080534572 , 468 Seiten
Format: PDF
Kopierschutz: DRM
Preis: 124,00 EUR
Cover
1
Contents
6
List of contributors
12
Preface
18
Acknowledgement
20
Section 1: Regulatory, effectory and accessory cells of the immune response
22
Chapter 1. Overcoming the TCR signalling defect of ß2-microglobulin deficient CD8+ T cells in response to wildtype syngeneic MHC class
24
Chapter 2. Adhesion molecules in the thymic microenvironment: interactions between thymocytes and cloned thymic epithelial cell lines
34
Chapter 3. Non-deletional tolerant state to a cognate antigen in TCR transgenic mice
56
Chapter 4. Thymus-targeted oncogene expression in TCR transgenic mice
68
Chapter 5. Effects of a unique adhesion-promoting anti-rat CD45 monoclonal antibody on T-cell activation
80
Chapter 6. Phenotype characteristics of NKR-P1+ cells in rats: correlation between presence of NKR-PI+/TCRa, ß– (NK) and NKR-P1/ TCRa, ß+ (NT) cells with Th-cell response
90
Chapter 7. LFA-1/ICAM-1 adhesion pathway is involved in both apoptosis and proliferation of thymocytes induced by thymic dendritic cells
98
Chapter 8. Apoptosis induced by microtubular poisons in thymocytes
108
Chapter 9. A monoclonal antibody R-MC 46 induces homotypic adhesion and activation of rat peripheral blood neutrophils
116
Chapter 10. Microenvironment of the rat thymus after cyclosporin treatment
124
Section 2: Molecular and cellular immunoregulatory mechanisms
134
Chapter 11. Antibody and protein glycosylation in health and disease
136
Chapter 12. Anti-DNA antibodies: is DNA the self antigen or a shelf antigen, or are all autoimmune diseases immunogen driven?
160
Chapter 13. Pathophysiology of Thl and Th2 responses in humans
170
Chapter 14. Monoclonal antibodies against idiotypes of human anti-insulin antibodies
188
Chapter 15. Effects of amyotrophic lateral sclerosis IgGs on calcium homeostasis in neural cells
194
Chapter 16. Strain-dependent induction and modulation of autoimmunity by mercuric chloride in two strains of rats
202
Chapter 17. An excess of IL-6 production in the early muscle stage of Trichinella spiralis infection in mice is associated with strain susceptibility to infection
210
Chapter 18. Naturally occurring anti-peptide antibodies in the rat: anti-Met-Enk antibodies
218
Chapter 19. Expression of Y7 idiotype on IgM molecules from cord sera
226
Chapter 20. Alterations in neonatal sexual differentiation affect T-cell maturation
234
Chapter 21. A study of human immunoglobulin (IgG and IgE) glycosylation by interaction with lectins
242
Chapter 22. Acute phase profile of novel plasma protein sgpl20 (PK–120)
256
Chapter 23. Total body irradiation-induced changes in rat serum IL-1, IL-6 and TNF activities
264
Section 3: Hypersensitivity and autoimmunity
272
Chapter 24. Two sources of programmed flexibility in the immune system: variation in structural and regulatory gene segments
274
Chapter 25. Down-regulation of Thl mediated autoimmune pathology
286
Chapter 26. Immunotherapy of atopic allergic diseases
300
Chapter 27. Altered functions of peripheral blood mononuclear cells and granulocytes in patients with active psoriasis
316
Chapter 28. CD4+ T lymphocyte subsets influence duration of clinical remission in recent-onset insulin-dependent diabetes mellitus
324
Chapter 29. Increased levels of TGF/ß1 in cerebrospinal fluid of multiple sclerosis patients
332
Chapter 30. Specificity and cross-reactivity of the 01 IgM mouse monoclonal antibody
338
Chapter 31. Humoral immune response to oxidized low-density lipoprotein in patients with coronary artery disease
346
Chapter 32. Biopsy-proven dilated heart muscle disease treated with immunomodulators: 2-year follow-up
352
Chapter 33. IL-1, TNF and IL-6 release by wound-inflammatory cells during the healing process in two strains of rats
360
Section 4: Host reactivity to graft, tumour and infection
368
Chapter 34. Cytotoxic mechanisms of natural killer cells
370
Chapter 35. MHC and other antigens at the feto-maternal interface
388
Chapter 36. Conserved bacterial proteins: implications for the pathogenesis of reactive arthritis
404
Chapter 37. Production and characterization of monoclonal antibodies antigens of Borrelia burgdorferi strain Košutnjak-K1
418
Chapter 38. Direct anticryptococcal activity of rat T cells
426
Chapter 39. Pro-IL-1ß processing is an essential step in the autocrine regulation of acute myeloid leukaemic cell growth
434
Chapter 40. Modulation of acute myeloid leukaemic cell growth by human macrophage inflammatory protein-la
442
Chapter 41. Interference at the respiratory burst level between the signals delivered in vitro in human peripheral neutrophils via fMLP, complement and Fc receptors
452
Chapter 42. HLA DQA1/DQB1 heterogeneity in DRBl*11/12 haplotypes in a Greek population
460
Chapter 43. Experimental trauma and the complement system
464
Chapter 44. Investigation of some factors that may modulate the activity of NK Cells
470
Index
478
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