Contrast Media - Safety Issues and ESUR Guidelines

von: Henrik Thomsen, Judith A. W. Webb

Springer-Verlag, 2009

ISBN: 9783540727842 , 254 Seiten

2. Auflage

Format: PDF, OL

Kopierschutz: Wasserzeichen

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Contrast Media - Safety Issues and ESUR Guidelines


 

Foreword

5

Preface to the 2nd Edition

6

Preface to the 1st Edition

7

Contents

9

General Issues

12

Classification and Terminology

13

Requests for Imaging Using Contrast Agents: What Information Must be Provided

20

Off-Label Use of Medicines: Legal Aspects

24

Pharmacovigilance: When to Report Adverse Reactions

29

What is Required in Order to Get the Authorities to Approve a New Contrast Agent?

32

A Critical Review of Meta-Analysis of Adverse Events After Contrast Agents

37

Iodinated and Gadolinium Contrast Media

46

Prevention of Acute Reactions

47

Management of Acute Adverse Reactions

56

Iodinated and Gadolinium Contrast Media

64

Contrast Medium-Induced Nephropathy

65

Dialysis and Contrast Media

83

Non-Insulin-Dependent Diabetes and Contrast Media

88

Iodinated and Gadolinium Contrast Media

94

Pregnancy and Lactation

95

Phaeochromocytoma

102

Interactions with Other Drugs and Clinical Tests

105

Extravasation Injury

112

Iodinated Contrast Media

117

Late Adverse Reactions

118

Effects on the Blood and Endothelium

123

Effect on Thyroid Function

133

Pulmonary Effects

141

MRContrast Media

147

Chelates and Stability

148

Diagnostic Efficacy

154

Radiography with Gadolinium Contrast Agents

163

MR Contrast Media

170

Acute Adverse Reactions

171

Delayed Reactions: Nephrogenic Systemic Fibrosis

176

MR Contrast Media

186

Gadolinium-Based Contrast Agents

187

Non- Gadolinium-Based Contrast Agents

193

Ultrasonographic Contrast Media

201

Safety of Ultrasonographic Agents

202

Barium Preparations

207

Barium Preparations: Safety Issues

208

Appendix

212

ESUR Guidelines on Contrast Media

213

Official Publications from the European Society of Urogenital Radiology

227

Subject Index

228

List of Contributors

236